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Prednisone forums: "Prednisolone is commonly used for several days before the needed effect is achieved. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Prednisone has very little mineral corticoid activity, so it is not used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Corticosteroids become exaggerated and may be observed as side effects of this medicine."
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