Prednisone has very little mineral corticoid activity, so it is not used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisone, are commonly used to suppress the immune system plays an important role. Prednisone is less likely than other corticosteroids to be secreted in breast milk, but it should be ensured that if antibiotics are required, that they are given in effective doses.
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