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Although Synthroid will speed up your metabolism, it is important to take it regularly at the same time every day. If you take Synthroid with an appetite-suppressant medication. Differences of only a few micrograms of Synthroid can make a large difference in how you feel. Aside from the treatment of hormone deficiency, you can take the Synthroid 50 mg tablet, which is made without color additives. Although this is rare. A too rapid increase in dosage.