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Valtrex is most effective when taken within 24 hours of the start of signs or symptoms. Valtrex is a very expensive drug if you do not have generic version called Valaciclovir. Valtrex is most effective if it is started within 48 hours of when the rash first appears. It can be passed on to sexual partners. Valaciclovir is an antiviral drug used in the management of herpes simplex and herpes zoster As you learn more about genital herpes, and also about Valtrex, the only once-daily medicine that can help reduce the number of outbreaks experienced in a year's time. How well Valaciclovir will work if you take it more than 24 hours after the start of signs or symptoms.
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